Isotopically Labeled Compounds
Medchemexpress LLC P-Tolualdehyde-d7 | 1219805-23-8 | 98.2% | 127.19 | 25 MG
P-Tolualdehyde-d7 is the deuterium-labeled p-Tolualdehyde. It is an active small molecule that can be used as a drug intermediate. This product is for research use only and is not sold to patients. Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes into drug molecules for quantitation during drug development.
Medchemexpress LLC L-Lysine-13C6,15N2 dihydrochloride | 202406-54-0 | 99.58% | 227.05 | 100 MG
L-Lysine-13C6,15N2 (dihydrochloride) is a 15N-labeled and 13C-labeled L-Lysine dihydrochloride. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Appearance: Solid
- Color: White to off-white
- Shipping: Room temperature in continental US; may vary elsewhere
- Storage: 4°C, sealed storage, away from moisture and light. In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
- Solubility (in vitro): DMSO: 125 mg/mL (550.54 mM; ultrasonic and warming and heat to 60°C); H2O: ≥ 100 mg/mL (440.43 mM)
![Revvity Health Sciences Inc Glycerol trioleate [9,10(N)-<sup>3</sup>H]-](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502811671.jpg-250.jpg)
Medchemexpress LLC Itraconazole-d3 | 1217512-35-0 | 99.6% | 708.65 | 5 MG
Itraconazole-d3 (R51211-d3) is the deuterium labeled Itraconazole, a triazole antifungal agent. It acts as a potent and orally active Hedgehog (Hh) signaling pathway antagonist, inhibiting lanosterol 14α-demethylase. Itraconazole also exhibits anticancer and antiangiogenic effects and is an oxysterol-binding protein (OSBP) inhibitor.
- Stable heavy isotopes of hydrogen, carbon, and other elements incorporated into drug molecules
- Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs
- Appearance: solid
- Color: white to off-white
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Colchicine-d3 | 1217625-62-1 | 99.2% | 402.46 | 1 MG
Colchicine-d3 is the deuterium labeled Colchicine. It acts as a tubulin inhibitor and a microtubule disrupting agent, effectively inhibiting microtubule polymerization with an IC50 of 3 nM. This compound also functions as a competitive antagonist of the α3 glycine receptors (GlyRs).
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Inhibits microtubule polymerization
- Competitive antagonist of α3 glycine receptors
Cayman Chemical StearIc AcId-d35 100mg
An internal standard for the quantification of stearic acid by GC- or LC-MS
Cayman Chemical Sphingosine Kinase Inhibitor
An SPHK1 inhibitor (IC50 = 0.5 µM for non-ATP-competitive inhibition of human recombinant SPHK1); selective for SPHK1 over ERK2, PI3K, and PKCα at 50s = 0.9-4.6 µM)
Medchemexpress LLC Norfluoxetine-d5 hydrochloride | 1188265-34-0 | 99.3% | 336.79 | 1 MG
Norfluoxetine-d5 (hydrochloride) is a deuterium-labeled compound. It can be used as a tracer and as an internal standard for quantitative analysis. Deuteration can affect pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated into drug molecules for quantitation during drug development.
- Deuteration can affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC ZLN005-d4 | 2410443-42-2 | 99.5% | 254.36 | 1 MG
ZLN005-d4 is a deuterium-labeled version of ZLN005. ZLN005 is a potent activator of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α).
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis through techniques such as NMR, GC-MS, or LC-MS
- Stable heavy isotopes, like deuterium, are incorporated into drug molecules and are used as tracers for quantitation during drug development
- Deuteration can influence the pharmacokinetic and metabolic profiles of drugs
American Radiolabeled Chemicals Inc 3H STNDRD GLASS-1 A
Tritium Standards on Glass Slides-1 each, 0-7390
American Radiolabeled Chemicals Inc INOSITOL MYO-3H 1LC
Inositol, myo-1,2-3H(N) 1mCi in ethanol:water (9:1), 1 mCi/ml, S.A 30-80 Ci/mmol, M.W. 180.2
Cambridge Isotope Laboratories Choline Chloride (Trimethyl-D9, 98%), 1g
Choline Chloride (Trimethyl-D9, 98%), 1037-86-3, HO(CH2)2N(CD3)3Cl, 148.68, 1g
American Radiolabeled Chemicals Inc 3H STNDRD GLASS-1
Tritium Standards on Glass Slides-1 each, 0-489.1
American Radiolabeled Chemicals Inc 3H STNDRD PLASTIC-1 A
Tritium Standards on Plastic Strips-1 each, 0-7390